Explore our challenge prizes
Want to help solve some of society’s biggest problems? You’re in the right place
This could be your opportunity to help solve some of the world’s biggest problems.
Challenge Works supports smart ideas and ingenious solutions, wherever they come from. We believe inventors can come from any background or sector, so we work to break down barriers, support long-term success and nurture innovation talent every step of the way.
We have worked with thousands of innovator teams and dozens of funders to find solutions to problems, draw attention to societal issues, and bring about real change.
Read on to find out more about our current and past portfolio of challenge prizes.

Longitude Prize on ALS
The Longitude Prize on ALS will open up data and utilise AI to identify and validate targets for transformative drug discovery.

Longitude Prize on Dementia
The Longitude Prize on Dementia sought the development of breakthrough technology that can learn from a person living with dementia, adapting and compensating for their condition as it progresses, and enabling them to continue living independently for longer.

Horizon Prize for the Reduction of Air Pollution Materials
Seeking the most affordable, sustainable and innovative design-driven material solution able to reduce the concentration of particulate matter in urban areas.

Horizon Prize for Better Use of Antibiotics
Improving antibiotics prescribing and reducing AMR through diagnostic tests.

Longitude Prize on Antimicrobial Resistance (AMR)
The Longitude Prize on AMR supported the development of a novel, affordable, accurate and rapid diagnostic tests to slow the development of antimicrobial resistance.

Mobility Unlimited Challenge
Supporting radical improvements in the mobility and independence of people with lower-limb paralysis through smarter assistive technology.

Covid-Safe Travel Challenge
Looking for solutions that leverage health and travel data to help increase confidence and enable a safe re-opening of London’s economy.

Global Surgical Training Challenge
Making simulation-based surgical training accessible through low-cost training modules.

Inclusive Technology Prize
Seeking to champion innovative assistive technology and encourage co-creation with disabled people.

Challenge prizes
Discover how challenge prizes work, why they attract the right innovators and how they can help solve urgent problems where solutions are lacking.
